Timely Topics in Transplantation Webinar Series
Speaker: Stephanie Pouch, MD • The Ohio State University Medical Center
Moderator: Shirish Huprikar, MD • Icahn School of Medicine at Mount Sinai
Multidrug-resistant organisms (MDROs) pose a particular threat to solid organ transplant recipients. Infections due to these pathogens are associated with significant morbidity and mortality, and current therapeutic options are limited.
After participating in this webinar, the learner will be able to:
- Describe the epidemiology and outcomes of select MDRO infections in solid organ transplant recipients.
- Describe an approach to the use of organs from donors colonized or infected with CRE.
- Discuss the role of infection control and antimicrobial stewardship in curtailing the spread of MDROs in solid organ transplant recipients.
Read Q&A that wasn't answered during the webinar
Free to AST members: $25 fee is waived upon logging in during the checkout process.
Explore the relevance of HLA testing before and after transplant in solid organ transplantation. At the end of this webinar, participants will be able to:
- Understand the enhanced methods of HLA typing and antibody detection now available before transplant
- Gain insight in determining recipient humoral risk profiles before and after transplant based on available testing
- Appreciate the limitations of HLA testing and the importance of context in interpretation
Explore the relevance of HLA testing before and after transplant in solid organ transplantation.
At the end of this webinar, participants will be able to:
- Understand the enhanced methods of HLA typing and antibody detection now available before transplant
- Gain insight in determining recipient humoral risk profiles before and after transplant based on available testing
- Appreciate the limitations of HLA testing and the importance of context in interpretation
Speaker: Jignesh Patel, MD • Cedars-Sinai Heart Institute
Moderator: Monica Colvin, MD, MS • University of Michigan
The presence of donor specific antibodies predisposes the thoracic allograft to the risk of antibody mediated rejection, chronic graft dysfunction and increased mortality. Optimal outcomes depend upon a comprehensive understanding of the significance of circulating antibodies after transplantation. What are the best strategies for defining deleterious antibodies, what are the current available therapies to address these and how effective are they?
- Identify the significance of circulating antibodies in patients awaiting thoracic transplantation or in patients with development of de novo antibodies after transplantation.
- Order appropriate tests to detect relevant donor specific antibodies.
- Design rational therapies for the treatment of post-thoracic transplant circulating antibodies.
Read Q&A that was not answered during the webinar
Free to AST members: $25 fee is waived upon logging in during the checkout process.
Join a transplant nephrologist, transplant surgeon, and epidemiologist as they discuss the risk of ESRD in living kidney donors focusing on two recent publications in JAMA and Kidney International. The presenters will provide:
- A brief overview of risks of living kidney donation known to date
- Discussion of the study design, methods and statistics in the manuscripts
- Implications of the manuscripts on living kidney donation and how to discuss risk with living donors in the context of this new information
Links to manuscripts:
- Abstract for Risk of End-Stage Renal Disease Following Live Kidney Donation (JAMA subscription required to view full article)
- Long-term Risks for Kidney Donors (Kidney International)
Join a transplant nephrologist, transplant surgeon, and epidemiologist as they discuss the risk of ESRD in living kidney donors focusing on two recent publications in JAMA and Kidney International. The presenters will provide:
- A brief overview of risks of living kidney donation known to date
- Discussion of the study design, methods and statistics in the manuscripts
- Implications of the manuscripts on living kidney donation and how to discuss risk with living donors in the context of this new information
- Understand the use and limitations of solid phase assays in identifying anti-HLA antibodies
- Describe the natural history and significance of DSA development post-transplant
- Discuss novel tools to improve specificity of solid phase assays
Free to AST members: $25 fee is waived upon logging in during the checkout process.
What you'll learn:
- Describe the common targets for direct acting antiviral therapy for HCV
- Understand current side effects and cure rates to therapy for HCV in liver transplant patients
- Discuss all oral DAA drug cocktails for HCV that can and will be used in the near future in transplant patients
What you'll learn:
- Describe the common targets for direct acting antiviral therapy for HCV
- Understand current side effects and cure rates to therapy for HCV in liver transplant patients
- Discuss all oral DAA drug cocktails for HCV that can and will be used in the near future in transplant patients
Read the Q&A that wasn't answered during webinar
Speaker: Rachel Patzer, PhD • Emory Universtiy
Moderator: Leo Riella, MD, PhD • Harvard Medical School
Significant barriers exist that may prevent patients from successfully navigating the complex transplant process to receive a transplant, including referral for transplant evaluation, starting the transplant evaluation, and completing the steps necessary to be placed on the national deceased donor waiting list or receive a kidney transplantation. There are several strategies and tools that transplant center physicians and staff members can use to improve patient access to transplantation and reduce disparities.
After participating in this webinar, the learner will be able to:
- Understand the key patient- and health system-related barriers in access to multiple steps of the transplantation process
- Evaluate the existing evidence-base of approaches for improving patient readiness and access to transplantation
- Identify potential solutions that transplant centers can implement to reduce disparities in transplantation access
Free to AST members: $25 fee is waived upon logging in during the checkout process.
What You'll Learn:
- Describe OPTN living donor policy requirements for the medical and psychosocial evaluation
- Describe OPTN policy requirements on living donor care, including requirements for follow-up, reporting, and the role of the independent living donor advocate (ILDA)
- Describe strategies to assist programs in monitoring compliance with living donor care requirements
Speaker: Mark Aeder, MD • University Hospitals Case Medical Center
Moderator: Nicole Turgeon, MD • Emory University
The Kidney Allocation System (KAS) was markedly revised on December 4, 2014, resulting in a major early alteration in national kidney distribution. Since a major objective was to provide equity in access to challenged candidates while not compromising vulnerable populations, and allowing for the bolus effects, this presentation will examine first year outcomes and assess the success in meeting the projected KAS goals.
After participating in this webinar, the learner will be able to:
- Identify the changes in kidney transplant distribution across recipient categories
- Distinguish the changes which will be maintained at a new level following the resolution of the initial bolus effect
- Begin to formulate potential modifications to KAS which would further achieve equity in allocation
Moderator: Nicole Turgeon, MD
Additional Q&A not covered during the webinar.
Free to AST members: $25 fee is waived upon logging in during the checkout process.
What You'll Learn:
- An update on the newly approved kidney allocation policy
- How to address implementation within your own transplant program
- What will this mean for patients currently on the list and those being currently evaluated
What You'll Learn:
- An update on the newly approved kidney allocation policy
- How to address implementation within your own transplant program
- What will this mean for patients currently on the list and those being currently evaluated